Intestinal-Specific TNFα Overexpression Induces Crohn’s-Like Ileitis in Mice
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چکیده
منابع مشابه
Intestinal-Specific TNFα Overexpression Induces Crohn’s-Like Ileitis in Mice
BACKGROUND AND AIM Human and animal studies have clearly established tumor necrosis factor (TNF)α as an important mediator of Crohn's disease pathogenesis. However, whether systemic or only local TNFα overproduction is required for the development of chronic intestinal inflammation and Crohn's disease remains unclear. The aim of this study was to assess the contribution of intestinal epithelial...
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ژورنال
عنوان ژورنال: PLoS ONE
سال: 2013
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0072594